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What are ketones?

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Ketones are lipid-derived, organic compounds that serve as a circulating energy source for tissues. Under normal physiological conditions with ample carbohydrates, Ketone concentrations are relatively low (~0.1-0.5mol/L), but in conditions of limited carbohydrate availability, or with Ketone supplementation with food and beverage, Ketone levels are increased and available from fatty acids converting into Ketones. The thermal energy, meaning the body’s energy from heat for metabolization, required to make use of Ketones is less than that of fats or carbs, contributing to the reason they are a compelling source of energy for athletes for endurance athletics, cognitive energy supplies from brain metabolism, and even in resting state.

How Do Ketones Work?

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Ketones are lipid-derived, organic compounds that serve as a circulating energy source for tissues. Under normal physiological conditions with ample carbohydrates, Ketone concentrations are relatively low (~0.1-0.5mol/L), but in conditions of limited carbohydrate availability, or with Ketone supplementation with food and beverage, Ketone levels are increased and available from fatty acids converting into Ketones.

How Do We Know It Works Scientifically?

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Are Ketones Safe?

Why would I take Ketones instead of strict fasting and high fat diet?

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The consensus from the scientific community is that Ketone drinks like ours offer a practical alternative to increase Ketone concentrations without as much rigorous adherence to a high fat, low carb, and fasting routine on an ongoing basis. For folks seeking level 5, our drinks help sustain and support these efforts and we applaud you {clap emoji}

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Scientific Citations

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Sato, K., Kashiw.aya, Y., Keon, C.A., Tsuchiya, N., King, M.T., Radda, G.K., Chance, B., Clarke, K., and Veech, RL. (1995). Insulin, ketone bodies, and mitochondrial energy transduction. FASEB J. 9, 651-658.

Cox, P.J., Kirk, T., Ashmore, T., Willerton, K., Evans, R., Smith, A., Murray, Andrew J., Stubbs, B., West, J., McLure, Stewart W., et al. (2016). Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metabolism 24, 1-13.

Stubbs, B.Cox, P.; Evans, R.; Santer, P.; Miller, J.; Faull, O.; Magor-Elliott, S.; Hiyama, S.; Stirling, M.; Clarke, K. (2017). On the metabolism of exogenous ketones in humans. Front. Physiol.

Cahill, G.F., Jr. (1970). Starvation in man. New Engl J Med 282, 668-675.

Murray, A.J., Knight, N.S., Cole, M.A., Cochlin, L.E., Carter, E., Tchabanenko, K., Pichulik, T., Gulston, M.K., Atherton, H.J., Schroeder, M.A., et al. (2016). Novel ketone diet enhances physical and cognitive performance. FASEB J.

Veech RL, Bradshaw PC, Clarke K, Curtis W, Pawlosky R, King MT. Ketone bodies mimic the life span extending properties of caloric restriction. IUBMB Life. 2017;69(5):305-314.